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Cholera

Vibrio cholerae

Vaccine-preventable4travelintestinal infectionsbacteriafood and water

Overview

Cholera is an acute intestinal infection caused by the bacterium Vibrio cholerae. Infection most often occurs after consuming contaminated water or food. Many cases are mild, but severe watery diarrhea can develop and lead to dehydration.

The most important step is prompt fluid replacement. For travelers, risk is higher in settings with limited access to safe water and sanitation.

Detailed Symptoms

Cholera primarily affects the gut and fluid/electrolyte balance.

- watery diarrhea - nausea and vomiting - muscle cramps (due to electrolyte loss) - intense thirst, dry mouth - weakness, dizziness

Symptoms

No symptom data available.

Treatment

Treatment focuses on rapid rehydration (oral rehydration salts or, in more severe cases, intravenous fluids) and electrolyte replacement. Antibiotics may be used in selected situations as decided by a clinician. Anti‑diarrheal medicines are not always appropriate—seek medical advice if unsure.

Course of Disease

Incubation is usually short (days). Illness can be mild or progress quickly—severe dehydration requires urgent medical care.

Complications

No complication data available.

Prevention Details

Best protection combines safe water and food practices with hygiene. For some travelers (e.g., visiting outbreak areas), vaccination may be an additional option after medical advice.

Prevention

No prevention data available.

Epidemiology

Cholera occurs in outbreaks in multiple regions, especially where safe water and sanitation are limited. Travel risk depends on destination, local hygiene standards, and current public‑health situation.

Risk Factors

Higher risk is associated with unsafe drinking water, raw foods, travel to areas with limited sanitation, humanitarian work, and crisis settings (e.g., after natural disasters).

Indications

- consider vaccination when traveling to outbreak areas or when exposure risk is higher - discuss prevention in a travel‑medicine clinic

Diagnosis

Diagnosis is guided by symptoms and exposure history (including travel) and can be confirmed with laboratory testing of stool samples.

Prognosis

With timely rehydration, outcomes are usually good. Delayed treatment increases the risk of complications in severe dehydration.

Names & Synonyms

Common Names

Cholera

Alternative Names

Vibrio cholerae infection

Content Warnings

This information is educational and does not replace medical advice. If you feel unwell, contact a clinician.

Review Information

Last reviewed by

SafeTripVax Medical Team

Review notes

Based on WHO and CDC guidance. Reviewed periodically as recommendations evolve.

Medical Information

Transmission
pokarmowa, wodna
Incubation Period
1 - 5 days
Causative Agent
Vibrio cholerae (bakteria)
ICD Codes
ICD-10: A00
Vaccine-preventable
Yes

Emergency Signs

signs of dehydration: very little urine, marked drowsiness, severe weakness
fainting or confusion
rapid deterioration
persistent vomiting preventing fluid intake

When to Seek Help

if diarrhea is profuse or rapidly worsening
if dehydration symptoms appear
if vomiting prevents adequate drinking
for children, older adults, and people with chronic conditions—seek help early

Prevention Measures

drink bottled or boiled water
avoid ice of unknown origin
eat thoroughly cooked food served hot
wash hands and use hand sanitizer
consider vaccination for higher‑risk itineraries

Contraindications

contraindications depend on the vaccine; they typically include a severe allergy to components
postpone vaccination during acute febrile illness (after medical advice)

Complications Details

Complications are mainly related to dehydration and electrolyte imbalance. Untreated severe dehydration can lead to shock and organ failure.

Travel Advice

check destination health advisories
pack oral rehydration salts (ORS)
start rehydration early if diarrhea begins
seek medical care if symptoms are severe or worsening

External Links

Also known as

Cholera